semaglutide not sleeping GLP-1s and Sleep?: How and Why Do GLP-1s Affect Sleep? Prescribing semaglutide for weight loss

Shared decision-making between patient and provider should weigh the medication's benefits against the burden of gastrointestinal adverse effects, exploring whether alternative GLP-1 receptor agonists or different therapeutic approaches might be better tolerated

These medications are available as injections or, as of December 2025, in oral pill form for certain FDA-approved products

Participants had an average age of 70 and took either a daily semaglutide pill or a placebo for about two years

Getting into the brain might also be important to treat neurodegenerative diseases where there are some promising results suggesting they slow disease progression

Some versions of compounded semaglutide treatments also use salt formulations that haven't been well-studied, she said