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In both patient populations with pre-existing cardiovascular disease, DPP-4 inhibitors are recommended as one possible third-line therapy besides SGLT-2 inhibitors, thiazolidinediones, or insulin, when therapeutic goals are not met with the previous dual combination

Evidence suggests that diabetes exacerbates the aggregation of -synuclein, a protein that accumulates in the brain in patients with PD, forming Lewy bodies

Neither medication is specifically a menopause medication, but both may be considered for weight management when clinically appropriate

Eat small, frequent meals rather than a few big ones

Metabolic inflammation