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Pharmacovigilance study of GLP-1 receptor agonists for metabolic and nutritional adverse events

The review also confirmed GLP-1s cardioprotective and neuroprotective effects, its ability to decrease inflammation and apoptosis, and its roles in learning and memory, reward behaviour, and food palatability via central GLP-1R-expressing circuits

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The level of VEGF-A significantly increased from 75.6 to 138.6 pg/mL in high glucose (HG)-stimulated human retinal endothelial cells (HRECs) but decreased to 102.1 pg/mL and 92.5 pg/mL with 50 nM and 100 nM liraglutide, respectively