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Second, the therapeutic response to anti-inflammatory and nephroprotective agents is highly variable among individuals, often hindered by poor bioavailability and rapid metabolic clearance [10]
Accessible surface area (ASA) calculations In order to predict potential epitope exposed to the immune system unshielded by glycosylation, the ASA was computed for each model as well as de-glycosylated model using FreeSASA according to the Lee & Richards algorithm 17
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