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Essentially, the FDA has not formally evaluated this exact mixture for safety/efficacy, but each ingredients effects are well-known

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Deficiency of vitamin B12 and its relation with neurological disorders: A review

Falsely increased values may be caused by myeloproliferative disorders or liver disease, whereas falsely low values can be seen with folate deficiency, pregnancy, multiple myeloma, and transcobalamin deficiencies

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