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The correct choice depends on whether your priority is maximum clinical certainty or accessibility under constraint

Andrea Bedrosian, director of bariatrics at North Shore University Hospital in Manhasset

Mistake 2: letting the vial touch the back wall Refrigerator back walls can drop below freezing, especially older models or refrigerators set to lower temperatures

Important safety considerations include the risk of pancreatitis (all GLP-1 agonists carry warnings about this), gallbladder disease (more common with greater weight loss), and a caution with semaglutide in patients with pre-existing diabetic retinopathy, where rapid improvement in glucose control may temporarily worsen retinopathy

Discussing a comprehensive medication review with your healthcare provider may identify opportunities for adjustment