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While the exact mechanisms remain to be fully elucidated, proposed pathways include modulation of dopamine release, suppression of neuroinflammation, and attenuation of stress-related neural circuits (27)
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174,175 Several oncogenic mechanisms, such as the transcription factor HIF-1, PI3K/Akt/mTOR pathway and c-Myc, upregulate genes encoding glucose transporters and glycolytic proteins, including GLUT1, GLUT3, and lactate dehydrogenase (LDH)
All this information will help them determine the most suitable course of medication management
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