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Most reactions are transient and decrease in frequency with continued use as patients develop tolerance
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Properties of the enzymes and regulation
They may turn out to work well just as GLP-1s, synthetic insulin, and EPO work
Some peptides support fat loss and body composition, while others enhance recovery, skin elasticity, cognitive clarity, or hormone balance
However, GLP-1 RAs are also associated with emerging cutaneous adverse drug reactions, including bullous, exanthematous and vasculitic manifestations, and other rare side effects
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