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A single mechanismeven HGF signallingmay be insufficient to address the complex cascade of tau pathology, inflammation, mitochondrial dysfunction, and vascular changes occurring in human disease

Additionally, oxidative stress can impair the clearance mechanisms of A, including autophagy and proteasomal degradation, contributing to its accumulation [154]

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There are a number of medical conditions and or medicines that may affect the decision to treat or the treatment plan

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