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The mechanism of action of DSePA against RP involved its ability to suppress the radiation-induced sustained inflammatory response by upregulating the pulmonary activity level of GPx and concurrently blocking the NF-kB/IL-17/G-CSF/neutrophil axis (Table 2) (Fig
Heavy metal detoxification Glutathione and its derivatives play a central role in heavy metal detoxification
10.1242/dmm.039552 220 MadillM.McdonaghK.MaJ.VajdaA.McloughlinP.ObrienT.et al
doi: 10.1159/000336803 376 SadatomiDNakashioyaKMamiyaSHondaSKameyamaYYamamuraYet al
In addition, the antidote, acetylcysteine plays an important role
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