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10.1016/s0022-3476(63)80221-8 J Pediatr
Low carnitine levels in the blood, particularly when combined with relevant clinical signs, support the diagnosis
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This astrocyteneuron lactate shuttle (ANLS), initially hypothesized by Pellerin and Magistretti, holds that BBB cells take up blood glucose via astrocytic/endothelial GLUT1 transport, allowing cerebral lactate buffering by astrocytic glycogen stores [56]
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