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In the mid-1990s, New York-based scientist John Eng discovered that the hormone exenatide isolated from the Gila monster, a venomous lizard mimicked the actions of GLP-1
Heat stroke / high body temperature
Major challenges associated with long-acting formulations include high material costs, limited biomaterial availability, and system complexity
Smith, J.A
Too much signal and the doseresponse curve flattens - you spend more money and expose yourself to more side effects for no extra benefit
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