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Timelines will depend on the specific medication or supplement as well as the specific type of surgery

Pregnancy and Breastfeeding: Most GLP-1 weight loss studies do not allow participation from pregnant or breastfeeding women due to unknown risks to the baby and potential hormonal effects

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With significant caloric restriction, studies show the body may reduce conversion of thyroid hormone T4 to the more active T3 form and alter sympathetic nervous system activity, both of which can influence heat production

Krhenbhl S, Reichen J