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One study found that direct recombinant IGF-1 LR3 administration at days 2, 5, and 7 accelerated muscle healing in mice with strain-injured muscles [1]
In a pilot study involving oncology patients receiving chemotherapy or radiotherapy, PYC supplementation (150 mg/day) was associated with a reduced frequency and severity of treatment-related side effects and decreased need for supportive medications
If side effects are severe or persistent beyond the first few weeks, your GP or diabetes specialist may suggest: Temporary dose reduction Anti-emetic medication for nausea Review of concomitant diabetes medications to reduce hypoglycaemia risk Alternative GLP-1 receptor agonist formulations if oral semaglutide remains poorly tolerated According to NICE guidelines (NG28) , treatment decisions should be individualised based on efficacy, tolerability, patient preference, and cost-effectiveness
And as of today, that is the only medication that has been approved ever
2020;383:1413-1424 Anker SD, et al
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