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Retatrutide (LY3437943) is a peptide developed by Eli Lilly that acts on three different metabolic receptors simultaneously: GLP-1 receptor GIP receptor Glucagon receptor This makes Retatrutide the first triple-agonist peptide to reach advanced Phase 3 clinical development
Glucagon-Like Peptide-1 Mechanism of Action on Gastric Function GLP-1 is a 30-amino acid peptide hormone secreted by enteroendocrine cells located in the mucosa of the distal part of the small intestine and colon [8]
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It exists in two forms: reduced (active) and oxidized
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