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Proper injection technique and monitoring can help reduce injection site discomfort

[15] [16] Patients with significant anaemia may need electrolyte monitoring, particularly in the first week of treatment

It is important to distinguish between excessive supplementation and pathologically elevated B12 levels, which may indicate underlying haematological disorders, liver disease, or renal impairment rather than true overdose

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Primary indications for B12 injections include: Pernicious anaemia is the most common indication in the UK