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Planning for long-term use, including the cost implications , is a practical necessity

At this time, there is not enough scientific evidence to consider it safe for use during pregnancy or breastfeeding, so avoiding it during these stages is generally recommended

If you experience headaches, irritability, or difficulty sleeping after taking glutathione, you're likely taking too much or too frequently

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The available data is one short-duration clinical trial in surgical patients (which found it well tolerated) and early pharmacokinetic work in healthy volunteers that did not flag acute harms