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Moreover, the BDNF Met 66 allele is associated with increased CSF concentrations of total tau and increased pTau concentrations in mutation carriers [159]
Its important to stress that while DSIP shows promise in addressing sleep disorders, human data are limited
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Patients with a prior history of serious gastrointestinal adverse events and other known risk factors that are associated with peptic ulcer disease ( alcoholism, smoking) are at increased risk
Botox injections, approved by the FDA for chronic migraine, may also help reduce muscle tension and headache frequency in select patients under medical supervision
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