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In the same study that evaluated semaglutide, liraglutide (Saxenda) resulted in a weight loss of approximately 5.4% during the STEP 1 trial
Bottom line: on a low-appetite day, the logging method that fits how you're actually feeling is the one that gets used
Specifically in regard to nausea, it tended to be most pronounced in the first 4 weeks of therapy in all phase III LEAD trials, with symptoms generally dissipating over the remainder of the study period
What the evidence actually supports: Preclinical efficacy and reasonable safety at tested doses
Alterations in oocyte mitochondrial number and function are related to spindle defects and occur with maternal aging in mice and humans
