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4 MASLD is now recognized as a multisystem disease: in addition to being strongly associated with type 2 diabetes mellitus (T2DM), it substantially increases the risk of developing T2DM itself, CVD, CKD, and extrahepatic malignancies, particularly colorectal cancer

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Ensure adequate protein intake (at least 0.8 grams per pound of body weight), prioritize sleep, and avoid dramatic calorie restriction during the transition

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