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BMJ 25(385):e078242 Pokharel Y, Khariton Y, Tang Y, Nassif ME, Chan PS, Arnold SV et al (2017) Association of serial Kansas City Cardiomyopathy Questionnaire assessments with death and hospitalization in patients with heart failure with preserved and reduced ejection fraction: a secondary analysis of 2 randomized clinical trials

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In one study in which calorie restriction failed to lower IGF-1 levels, researchers asked six volunteers to reduce their daily protein intake