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45 Degrees vs 90 Degrees: Choosing the Right Angle The 45-degree angle is appropriate when the subcutaneous fat layer is thin, specifically when the pinch technique is used or when injecting at a site with limited adipose tissue

Starting at 2 mg and escalating slowly is KEY, as the Phase 2 data showed a lower starting dose of 2 mg produced meaningfully fewer GI side effects than jumping in at 4 mg

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