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It is also a co-factor for several metabolic enzymes is involved in intracellular transport, functions as an antioxidant and radioprotectant and facilitates protein folding and degradation
Still, that effect did not replicate at scale in the larger, longer Phase IIb study designed to confirm it which is the standard reason a compounds development gets discontinued rather than a sign the compound is unsafe
It received GRAS (Generally Recognized as Safe) status for use as a food ingredient, which is a separate regulatory category
Should the injection be administered before or after physical activity in a study
However, after synthesizing and testing a set of PROTACs this strategy was not successful
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