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Other factors, including patient age, gender, body mass index (BMI), and hepatitis C infection, further exacerbate the risk of PTDM. Current management of PTDM remains a challenge, often requiring adjustment immunosuppressant regimens and promoting lifestyle changes
Elevated homocysteine often correlates with reduced glutathione levels , creating a vicious cycle: Homocysteine rises Glutathione production falls Oxidative stress increases Inflammatory cytokines activate Breaking this cycle by restoring redox balance appears to be a critical step in reducing inflammatory signaling