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We're talking about conditions that dramatically slow down the degradation processes we just discussed
Reduced glutathione achieves this by attenuating ROS, which is important in the context of inflammation because ROS stimulates the activity of these proinflammatory cytokines
In order to limit the release of payloads before internalization, preventing or minimizing degradation outside the target cell, the proteome of the lysosome became a logical place to search for enzymes capable of ADC degradation and present in high concentration
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Your peptide protocol doesnt exist in a vacuum
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