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A clinical trial studies a drug under strict research rules
Vettore L, Westbrook RL, Tennant DA
Reduced food intake must first deplete your body's stored energy (glycogen and fat) before scale weight changes noticeably
Other common side effects include diarrhea, constipation, headache, fatigue, and dizziness, among others
Common Side Effects Reported Across Phase 2 trials, participants experienced dose-dependent GI symptoms that are characteristic of GLP-1 receptor agonists: Nausea most frequent, especially during dose escalation Vomiting typically mild to moderate, subsiding with continued use Diarrhea and constipation fluctuating depending on individual tolerance Abdominal discomfort transient and often improved over time Dose-Response Relationship At lower doses (14 mg weekly), side effects were generally mild and manageable, though some participants still reported early GI symptoms
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