An increased proportion of PUFAs in normal diet also induces oxidative stress (increased malondialdehyde [MDA]), reduces cellular defense against oxidative stress (metallothionein) in the liver, and promotes oxidative degradation of DNA (elevated 8-hydroxy-2-deoxyguanosine levels serum) in a content-dependent manner despite increased fat oxidation and decreased fat synthesis [80]
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PubMed laboratory research record [PMID: 15791917] PubMed record related to this compound for laboratory literature review
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If a patients disease is more severe or theyre not getting to their A1c goal with those classes, at that point a PCP might refer a patient to an endocrinologist for treatment with insulin or GLP-1s, which are injected