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The proposed mechanism is increased BDNF expression plus effects on dopamine and norepinephrine
Potential Side Effects Not all effects are positive
Some are coming off insulin entirely because their diabetes has effectively reversed
We found that cisplatin treatment caused a decrease in mitochondrial biogenesis (PGC-1, NRF-1, TFAM, mtDNA, ND1), mitochondrial mass (Porin and Citrate synthase activity) and fusion index (MFN2, Drp1), together with changes in the expression of autophagy-related genes (AKT/FoxO pathway, Atg1, Beclin1, LC3AII, p62) and enhanced ROS production (PRX III, MnSOD)
Individual timelines vary depending on the condition being treated, dosage, and overall health
