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Conclusions This is the first known study using NAC as a treatment for acute opioid withdrawal in the neonatal rat
However, their effectiveness still needs to be explored over a longer period of time
FIGURE 1 5.1 Upregulation of antioxidant response elements and metabolic pathways in the mitochondria 5.1.1 NRF2 inducers NRF2 (Nuclear factor Erythroid 2-related Factor 2) is a transcription factor involved in the expression of antioxidant enzymes which contain the ARE (Li et al., 2019)
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