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In addition, long-term adherence to a KD can lead to loss of appetite, gastrointestinal discomfort, and other side effects (125), however, the elderly often suffer from possible concomitant diseases such as diabetes and malnutrition, which affects compliance and limits the application of KD (126)
Nature Reviews Drug Discovery, 21(8), 579-598
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TB-500 is associated with more systemic effects, including angiogenesis, cell migration, and broader anti-inflammatory action
In many of these cases, altered renal function has been reversed with supportive treatment and discontinuation of potentially causative agents
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