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The most common adverse reactions reported in clinical trials were injection site reactions (erythema, pruritus, pain) occurring in approximately 8-13% of patients

For leaner individuals or areas with less subcutaneous fat (like the abdomen), the shorter 5/16" needle is often a superior choice

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At the 12mg maintenance dose, retatrutide produced significant reductions in systolic blood pressure of approximately 57 mmHg from baseline by week 24

Landmark roughly two to three finger-widths below the acromion process, into the densest part of the muscle, well clear of the shoulder bursa