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These mechanistic perspectives provide potential explanations for some of the clinical improvements seen and illustrate the various pathways through which FMT might exert its effects on disease processes

Straining during bowel movements increases intra-abdominal pressure, predisposing to haemorrhoidal bleeding

Starting July 1, 2026, eligible people with Medicare Part D coverage may qualify for certain GLP-1 weight-loss medications through a new CMS program called the Medicare GLP-1 Bridge

Low urinary pH predisposes for uric acid precipitation since the pKa of uric acid is 5.7, therefore the solubility of uric acid decreases with low pH, and thus increasing the risk of kidney stones (44)