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Once weekly dulaglutide had the most total adverse events, but the lowest percentage of cutaneous adverse events at 3.75%, which researchers noted could be due to greater prescription rates rather than increased dermatologic risk

This is metabolic adaptation, not injection failure

Potential for Long-Term Sustainability Some patients might find microdosing easier to maintain, as it is less intimidating, carries fewer potential side effects, and offers a moderate pace, making it feel more sustainable in the long run

Follow facility SOPs for multidose vial handling