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The peptide appears to promote cell migration and angiogenesis, key processes in tissue repair
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We used an inducible model that with administration of tamoxifen allowed us to temporally delete the IGF1R after Nestin + cells in the brain had reached the quiescent phase but at a time point in which the skeleton continues to undergo rapid growth
Once inside the mitochondrial matrix, a second enzyme, Carnitine Palmitoyltransferase 2 (CPT2), detaches the L-Carnitine, releasing the fatty acid so it can undergo beta-oxidationa process that breaks down the fat into acetyl-CoA
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