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Results 3D gels selectively support the survival of a subset of lymphoid tumor cells While growth rates of LCLs (X50-7 and JY) and lymphoma B cells (DG-75 and BL-2) in 2D culture conditions are nearly identical [28], lymphoma B cells form colonies within 3D gels, unlike LCLs (Fig

Mild hyperthermia enhanced synergistic uric acid degradation and multiple ROS elimination for an effective acute gout therapy

By synthesizing BH4 via GCH1 and subsequently reducing dihydrobiopterin (BH2) to BH4 through dihydrofolate reductase (DHFR), BH4 functions as an endogenous anti-ferroptotic RTA[39]