tirzepatide semaglutide dose conversion GLP-1 vs Dosing: Clinical Equivalency Guide – PlexusDx switching from tirzepatide to semaglutide

There is, however, evidence to support considering closer follow-up when initiating a GLP-1 RA, particularly if rapid improvement in glycemic control is anticipated, following a baseline dilated fundus examination performed around the time of therapy initiation

Clinicians should highlight dehydration risk and reinforce the importance of maintaining adequate fluid intake, especially as patients who experience nausea on GLP-1 medications may avoid consuming fluids. Clinicians should also use caution prescribing these medications in patients with diminished gastrointestinal motility

When tirzepatide is listed as in shortage, 503A compounding is explicitly permitted

1 Attach & prime Wipe the pen tip with an alcohol swab and screw on a fresh needle

For patients with type 2 diabetes, do not abruptly discontinue all diabetes medications if tirzepatide must be discarded