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J Biol Chem 265:80018008 Nauck MA, Bartels E, Orskov C, Ebert R, Creutzfeldt W (1993a) Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at near-physiological insulinotropic hormone and glucose concentrations
When partially digested food sits in the fundus longer than normal, mechanoreceptors and chemoreceptors send distension and acidity signals to the area postrema and nucleus tractus solitarius in the brainstem
Patients on a maximum dose of semaglutide lost 80% fat mass and only 20% lean mass
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