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ClinicalTrials.gov registration: NCT04889183

Compounded drugs can be important for overcoming shortages or meeting unique patient needs, but compounders should not try to compound drugs in a way that circumvents the FDAs approval process. Related: Prescription for Change: DTC Pharma Advertising Could Face Major Crackdown This marks the second wave of warnings since the Trump administrations crackdown on misleading direct-to-consumer (DTC) pharmaceutical ads in September 2025

A recent Sermo survey of hundreds of United States-based physicians indicate that almost half of the responding doctors reported that patients disclosed use of unapproved peptides in the past year

Randomized, placebo-controlled comparison of amitriptyline, duloxetine, and pregabalin in patients with chronic diabetic peripheral neuropathic pain: impact on pain, polysomnographic sleep, daytime functioning, and quality of life