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Data were processed using GraphPad Prism 8 software (GraphPad software Inc., San Diego, CA, USA), and differences between groups were analyzed by unpaired Students t test or one-way analysis of variance (ANOVA)
At this level, two different preparations (C1 and C2) were followed
The musculoskeletal side effects include muscle pain, muscle weakness, cramps and swelling in extremities including hands, arms, ankles, feet and/or lower legs
The starting dose of 0.3 mg represents approximately 6.7% of the final maintenance dosea conservative approach that prioritizes safety
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