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TB-500 is the synthetic tetrapeptide fragment Ac-SDKP, corresponding to the actin-binding domain of thymosin beta-4
Typically made into a skin cream or scalp lotion and used for anti-aging and cosmetic purposes, it may also help heal wounds such as diabetic ulcers and traumatic wounds with reduced scarring
In good agreement with this role, genome-wide association studies correlated SNPs occurring at the level of SLC16A9 gene, with carnitine, propionylcarnitine and urate levels in serum (Kolz et al., 2009
In addition to biocompatibility, biodegradation, bioadhesiveness, and biofunctionality of the NDBs, several drawbacks must be addressed, such as low stability, low melting point, high surface tension, structural complexity, and well-known immunological response from organisms (Ige et al., 2012
But the current crop of synthetic peptides comes with the promise of astronomical profit
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