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193 In a study that included 1,886 community-dwelling individuals between 60 and 91 years old, those with the lowest DHEA-S levels within their gender group had a 50% higher chance of being frail than those with the highest levels

Who Should Be Cautious About Using Healing Peptides Alone A conservative approach matters most in these groups: People with unclear diagnosis (pain without a clear tissue source) Those with systemic inflammatory conditions and frequent flares Individuals on complex medication regimens where interactions and contraindications matter People with a history of malignancy who need careful risk framing Anyone seeking a passive fix while ignoring rehabilitation and lifestyle structure Cautious does not mean never. It means the bar for oversight, sequencing, and monitoring should be higher

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This is significant because 90% of the bodys serotonin is produced in the gut