If a dose is missed, the FDA labeling instructs patients to administer the missed dose as soon as possible if within 4 days (96 hours) of the scheduled time
doi:10.1007/s00394-019-02014-4 Hosoe K, Kitano M, Kishida H, Kubo H, Fujii K, Kitahara M
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The answer depends entirely on vial type, total medication, concentration, and your weekly dose
The assessment was performed at intervals before, during, and after therapy