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Hasty P, Sharp ZD, Curiel TJ, Campisi J

A Mayo Clinic study published in a major medical journal found that postmenopausal women using semaglutide in combination with hormone replacement therapy achieved approximately 30 percent more weight loss compared to semaglutide alone

If you experience significant side effects early on, genetic context can help determine whether slower escalation, dietary adjustments, or even a switch to an alternative GLP-1 formulation (such as oral compounded semaglutide or compounded tirzepatide) might be more suitable for your physiology

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