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According to the textbook, synapses only exist between neurons, and specialized sensory cells such as gustatory cells 75,76,77 and hair cells 78
These include findings that treatment with oral semaglutide significantly reduced hospitalisations related to serious adverse events compared with placebo
When activated, GLP-1 signaling can reduce neuroinflammation and stabilize serotonin levels, both of which are implicated in migraine biology
Additionally, its central effects extend to reward pathways, reducing cravings and hedonic eating, which contributes significantly to weight loss in individuals with obesity[8]
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