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Mechanistically, valproate may cause somnolence by inhibiting the reuptake of GABA (and thereby potentiating GABA signaling in the brain)
Therefore, complex mechanisms in both neurons and astrocytes may be involved in GLP-1-induced modulation of food intake in the NTS
Understanding how semaglutide interacts with the digestive system may help patients and healthcare providers better manage treatment expectations and potential gastrointestinal effects
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