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Exenatide (twice-daily) and lixisenatide are GLP-1 receptor agonists based on exendin-4 that overcome cleavage by DPP-4, however, their half remains short with ~ 24 h due to renal elimination
This direct delivery method theoretically provides higher bioavailability, meaning more of the active compound reaches target tissues
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Below is a list of common side effects associated with GLP-1 receptor agonists, as noted by the FDA-issued package inserts for approved GLP-1 medications: Decreased Appetite: Many users experience a reduced desire to eat, which can aid in weight loss
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