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Dynamic light scattering indicates homogenous particles (PDI as low as 0.084) for uniform delivery

Copper (Cu) is essential for the activation of superoxide dismutase (SOD, antioxidant defense), lysyl oxidase (collagen cross-linking), and wound-healing enzymes

In contrast, LECs express genes involved in the formation and maintenance of LVs, such as PROX1 , Podoplanin (PDPN) , Lymphatic vessel endothelial hyaluronan receptor 1 ( LYVE1 ) and FLT4 ( Table 1 )

5 During the premonitory stage up to 3 days before headache, tiredness, mood changes, yawning, thirst, cravings, urinary frequency, light and sound sensitivity, and cranial autonomic symptoms may occur, while symptoms in the postdrome phase up to 48 hours post-headache include tiredness and difficulty concentrating