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after stimulation of SMase-dependent ceramide formation, assembly of the death-inducing signaling complex (DISC) and oligomerization of Fas receptor, as well as cleaved caspase-8 and caspase-3, were detected [130]

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We then summarize the multilayer regulation of FSP1 and discuss how it contributes to ferroptosis resistance, tumor adaptation, and therapeutic responses in cancer

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The studies on use in other diseases such as psoriasis, pemphigus vulgaris, acne vulgaris, rosacea, etc