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It is part of Dale Bredesen's "Cognoscopy" protocol for evaluating brain and cognitive health, validated for ages 8-89 with a 4th grade reading competency
2b, Extended Data Fig
Studies have also not indicated any efficacy of B12 injections in improving cognitive function or mental health
A person taking high-dosage supplements of folic acid may be able to correct the anemia and feel better, but the B12 deficiency still exists
10.3390/nu16162660 Summary Keywords curcumin, depressive, anxiety, chronic disease, co-occurring disorders Citation Yuan J, Pi C, Shen H, Zhou B, Wei Y, Dechsupa N and Zhao L (2025) Potential therapeutic benefits of curcumin in depression or anxiety induced by chronic diseases: a systematic review of mechanistic and clinical evidence
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