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Accumulating evidence has highlighted that APAP-induced oxidative stress and mitochondrial dysfunction are the fundamental factors in the pathogenesis of APAP-associated liver injury (ALI)
T.SantamariaA.BowmanA
An enzyme called tyrosinase is needed to create melanin (the pigment that causes the brown spots) and while several other skin lightening agents work to inhibit the synthesis of tyrosinase itself (like vitamin C or licorice), arbutin lets tyrosinase be and rather hinders the melanin-forming activity of the enzyme
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Systemic glutathione as a skin-whitening agent in adult
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